GATA Binding Protein 3 Antibody / GATA-3

GATA Binding Protein 3 Antibody / GATA-3

• Description: GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas.
• CAS Number: 9007-83-4
• UniProt: P23771
• Host: Mouse
• Immunogen: Recombinant full-length human protein was used as the immunogen for the GATA Binding Protein 3 antibody.
• Clonality: Monoclonal
• Isotype: IgG2b κ
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the GATA Binding Protein 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This GATA Binding Protein 3 antibody is available for research use only.