FABP4 Antibody

CAT: 0800-V9495SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V9495SAF-100UGSize:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP) . The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P15090
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 1-132 was used as the immunogen for the FABP4 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
FABP4/4426
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the FABP4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FABP4 antibody is available for research use only.
Storage Conditions
Aliquot the FABP4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the FABP4 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
IHC staining of FFPE human breast carcinoma tissue with FABP4 antibody (clone FABP4/4426) at 2ug/ml in PBS for 30min RT. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Product Datasheet
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