Fibroblast Activation Protein Alpha Antibody / FAP | Gentaur

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Alternative Products

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abx129431-50ug	Fibroblast Activation Protein Alpha (FAPa) Antibody
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abx172378-50ug	Fibroblast Activation Protein Alpha (FAPa) Antibody

Fibroblast Activation Protein Alpha Antibody / FAP

CAT:

800-V9470-100UG

Size:

100 µg

Price:

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For price, please contact [email protected].

Fibroblast Activation Protein Alpha Antibody / FAP

Description: FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is colocalized with MMP-1 and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.
UniProt: Q12884
Host: Mouse
Immunogen: A portion of amino acids 1-200 was used as the immunogen for the Fibroblast Activation Protein Alpha antibody.
Clonality: Monoclonal
Isotype: IgG2c κ
Applications: IHC-P
Format: Purified
Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution: Aliquot the Fibroblast Activation Protein Alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations: This Fibroblast Activation Protein Alpha antibody is available for research use only.

Complementary Product Range

Our range of products, including Fibroblast Activation Protein Alpha Antibody / FAP, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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