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CML66 Antibody / NUDCD1

CAT: 0800-RQ8413Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8413Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NudC domain containing 1 (NudCD1), also known as CML66 (Chronic myelogenous leukemia tumor antigen 66), is a protein initially identified as overexpressed in patients with chronic myelogenous leukemia. The mRNA of NudCD1 is expressed in heart and testis of normal tissues, and is overexpressed in several cancers. The expression level of the protein correlates with tumoral phenotype, possibly interacting upstream of the Insulin Growth Factor - 1 Receptor (IGF-1R) . The gene encoding the NudCD1 protein consists of 12 exons that can be alternative spliced, leading to the expression of three different isoforms. These isoforms possess a common region of 492 amino acids in their C-terminus region and have an isoform specific N-terminus.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
Q96RS6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (Q72-K578) was used as the immunogen for the CML66 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CML66 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CML66 antibody is available for research use only.
Storage Conditions
After reconstitution, the CML66 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CML66 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
IHC staining of FFPE human ovarian cancer tissue with CML66 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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Alternative Products

CatalogName
039197NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66)
MBS6327098-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (FITC)
MBS6327096-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (APC)
MBS6327105-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (PE)
MBS6327097-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (Biotin)
MBS6327095-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (AP)
039197-FITCNUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (FITC) discontinued
MBS6327104-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (MaxLight 750)
MBS6327102-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (MaxLight 550)
MBS6327101-01NUDCD1, ID (NUDCD1, CML66, NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66) (MaxLight 490)

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