MYT1L Antibody / Myelin transcription factor 1-like protein

MYT1L Antibody / Myelin transcription factor 1-like protein

• Description: Myelin transcription factor 1 like is a protein that in humans is encoded by the MYT1L gene. This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants.
• CAS Number: 9007-83-4
• UniProt: Q9UL68
• Host: Rabbit
• Immunogen: An E.coli-derived human recombinant protein (D195-K825) was used as the immunogen for the MYT1L antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IF, FACS, ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the MYT1L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This MYT1L antibody is available for research use only.