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MEKK4 Antibody / MAP3K4

CAT: 0800-RQ8344Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8344Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
Q9Y6R4
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide derived from human Mitogen-activated protein kinase kinase kinase 4 protein was used as the immunogen for the MEKK4antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28M41
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the MEKK4 antibody at -20oC.
Limitations
This MEKK4 antibody is available for research use only.
Storage Conditions
Store the MEKK4 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the MEKK4 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 293T cell lysate with MEKK4 antibody. Predicted molecular weight: 177-182 kDa (two isoforms) .

UniProtKB · Q9Y6R4

Mitogen-activated protein kinase kinase kinase 4

M3K4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6R4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP3K4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.25
Processing
—
Secondary accessions
A6H8W0, B7ZLD3, B9EG75, Q5VTT8, Q5VTT9, Q92612, Q9H408
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cytoplasm

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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