Products for Research Use Only

Phospho-CBL Antibody (pY774)

CAT: 0800-RQ8272Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ8272Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Casitas B-lineage lymphoma proto-oncogene / CBL is an adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P22681
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide derived from the area surrounding phosphorylated tyrosine 774 of human CBL was used as the immunogen for the Phospho-CBL antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28C29
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Phospho-CBL antibody at -20oC.
Limitations
This Phospho-CBL antibody is available for research use only.
Storage Conditions
Store the Phospho-CBL antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Phospho-CBL antibody should be determined by the researcher.
Image Legend
Western blot testing of lysate from pervanadate-treated human Jurkat cells with Phospho-CBL antibody.

UniProtKB · P22681

E3 ubiquitin-protein ligase CBL

CBL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22681
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CBL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
A3KMP8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMetal-bindingZinc

Cellular component

Cell membraneCell projectionCytoplasmGolgi apparatusMembrane

Disease

Disease variantProto-oncogene

PTM

PhosphoproteinUbl conjugation

Domain

RepeatZinc-finger

Molecular function

Transferase

Biological process

Ubl conjugation pathway