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Ninein Antibody / NIN

CAT: 0800-RQ8214Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8214Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ninein is a protein that in humans is encoded by the NIN gene. This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8N4C6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids Q1023-H2090) was used as the immunogen for the Ninein antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Ninein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Ninein antibody is available for research use only.
Storage Conditions
After reconstitution, the Ninein antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Ninein antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of fixed and permeabilized human MCF7 cells with Ninein antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Ninein antibody.

UniProtKB · Q8N4C6

Ninein

NIN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N4C6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NIN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hNinein
EC number
—
Processing
—
Secondary accessions
A6NDB8, B7WPA3, C9JSB6, C9JSG2, C9JXL2, Q5BKU3, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCytoplasmCytoskeletonMicrotubule

Domain

Coiled coilRepeat

Disease

Disease variantDwarfismIntellectual disability

Ligand

GTP-bindingNucleotide-binding

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome
Product Datasheet
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