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PRP31 Antibody / PRPF31

CAT: 0800-RQ8092Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8092Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8WWY3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids K73-K488) was used as the immunogen for the PRP31 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the PRP31 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PRP31 antibody is available for research use only.
Storage Conditions
After reconstitution, the PRP31 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PRP31 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Immunofluorescent staining of FFPE human A549 cells with PRP31 antibody (red) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q8WWY3

U4/U6 small nuclear ribonucleoprotein Prp31

PRP31_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WWY3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRPF31
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E7ESA8, F1T0A4, F1T0A5, Q17RB4, Q8N7F9, Q9H271, Q9Y439
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Disease

Disease variantRetinitis pigmentosa

Biological process

mRNA processingmRNA splicing

Cellular component

NucleusSpliceosome

Molecular function

RibonucleoproteinRNA-binding

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