CDC42 Antibody

CAT: 0800-RQ8037Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ8037Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P60953
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids N26-L191) was used as the immunogen for the CDC42 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CDC42 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CDC42 antibody is available for research use only.
Storage Conditions
After reconstitution, the CDC42 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CDC42 antibody should be determined by the researcher.
Location
Cytoplasm, cell membrane
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with CDC42 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.
Product Datasheet
Loading...

Related Products

CatalogName
F50698-0.08MLACK1 Antibody / Activated CDC42 kinase 1
F50698-0.4MLACK1 Antibody / Activated CDC42 kinase 1
RQ7565Activated CDC42 kinase 1 Antibody / ACK1
RQ4490CDC45 Antibody
RQ4758CDC40 Antibody
V3748-20UGCDC2 Antibody / CDK1
RQ5144CDK1 Antibody / CDC2
F50473-0.08MLCDC2 Antibody / CDK1
V3040-20UGCDC2 Antibody / CDK1
F53812-0.05MLCDK1 Antibody / CDC2

Alternative Products

CatalogName
MBS852469-01CDC42 Antibody

Popular Products