Tocilizumab Biosimilar - Research Grade
CAT:
1148-ICH4012-20mg
Size:
20 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tocilizumab Biosimilar - Research Grade
- Background: Tocilizumab is a recombinant humanized anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin IgG1κ (gamma 1, kappa) subclass with a typical H2L2 polypeptide structure. Each light chain and heavy chain consists of 214 and 448 amino acids, respectively. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds. Tocilizumab has a molecular weight of approximately 148 kDa. The antibody is produced in mammalian (Chinese hamster ovary) cells.
- Specifications: Detects human IL-6 receptor. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Tocilizumab.
- Product Name Alternative: IL6R
- UniProt: P08887
- Host: Humanized
- Species Reactivity: Human
- Target: IL-6 receptor
- Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- Concentration: 1.0 - 5.0 mg/mL
- Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
- Purity: >95% by SDS-PAGE and HPLC
- Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
- Shipping Conditions: Blue ice
- Storage Conditions: Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Formulation: Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
- Isotype Control: https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/