Anti-Rat CD71 (OX-26) In Vivo Antibody - Ultra-Low Endotoxin

• Background:

  CD71 is a transferrin receptor on the cell surface that mediates the uptake of transferrin-iron complexes, thereby mediating cellular proliferation. CD71 is a homodimeric glycoprotein containing 760 amino acids and it binds to diferric transferrin. Binding by diferric transfferin causes CD71 to be internalized, and diferric iron is subsequently released. CD71 is highly expressed on malignant cells, as iron uptake is necessary for aberrant cell proliferation.

• Specifications:

  Clone OX-26 reacts with mouse and rat CD71 (TfR1).

• Host:

  Mouse

• Species Reactivity:

  Mouse, Rat

• Target:

  CD71

• Isotype:

  IgG2a

• Clone:

  OX-26

• Applications:

  Flow Cytometry,Immunohistochemistry

• Purification Method:

  This monoclonal antibody was purified using Protein A

• Concentration:

  ≥ 2.0 mg/mL

• Endotoxin:

  ≤ 0.5 EU/mg as determined by the LAL method

• Purity:

  >98% by SDS-PAGE and HPLC

• Buffer:

  ICH3001-100mL ICH3002-100mL ICH3003-100mL

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

• Formulation:

  Sterile, preservative-free, solution in PBS. BSA and Azide free.

• Antigen Distribution:

  CD71 is expressed on the surface of proliferating cells, reticulocytes, and erythroid precursors.

• Aggregation:

  Aggregation level ≤ 1%

• Applications Notes:

  Each investigator should determine their own optimal working dilution for specific applications.

• Isotype Control:

  https://ichor.bio/product/mouse-igg2a-in-vivo-isotype-control-low-endotoxin-c1-18-4-ich2245/

• CAS Number:

  9007-83-4