Anti-Mouse IFN Gamma (XMG1.2) In Vivo Antibody - Low Endotoxin

• Background:

  Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. IFNG has antiviral, immunoregulatory, and anti-tumour properties.

• Specifications:

  Anti-IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2) recognizes an epitope on Mouse IFN-gamma

• Product Name Alternative:

  Interferon gamma, Ifng

• UniProt:

  P01580

• Host:

  Rat

• Species Reactivity:

  Mouse

• Target:

  IFN gamma

• Isotype:

  IgG1

• Clone:

  XMG1.2

• Applications:

  ELISA Capture, ELISPOT, IHC (Frozen), Neutralization, Western Blot, CyTOF

• Purification Method:

  This monoclonal antibody was purified using Protein G

• Concentration:

  1.0 mg/mL

• Endotoxin:

  <1.0 EU/mg as determined by the LAL method

• Purity:

  >95% by SDS-PAGE and analyzed by silver stain.

• Buffer:

  ICH3001-100mL ICH3002-100mL ICH3003-100mL

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Anti-IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

• Formulation:

  0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

• Aggregation:

  Aggregation level ≤ 5%

• Applications Notes:

  Each investigator should determine their own optimal working dilution for specific applications.

• Isotype Control:

  https://www.ichor.bio/product/Rat-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-GL113-ICH2246

• CAS Number:

  9007-83-4