Anti-Mouse CD120a (55R-170) In Vivo Antibody - Low Endotoxin

• Background:

  Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated. TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses. It regulates immune and inflammatory responses.

• Specifications:

  Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-170) recognizes an epitope on Mouse TNF RI

• Product Name Alternative:

  Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60

• UniProt:

  P25118

• Host:

  Armenian Hamster

• Species Reactivity:

  Mouse

• Target:

  CD120a

• Isotype:

  IgG1

• Clone:

  55R-170

• Applications:

  Immunoprecipitation, Western Blot, Blocking, Functional Assays, Flow Cytometry, Neutralization

• Purification Method:

  This monoclonal antibody was purified using Protein A

• Concentration:

  1.0 mg/mL

• Endotoxin:

  ≤ 1.0 EU/mg as determined by the LAL method

• Purity:

  >95% by SDS-PAGE and HPLC

• Buffer:

  ICH3001-100mL ICH3002-100mL ICH3003-100mL

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-170) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

• Formulation:

  0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

• Aggregation:

  Aggregation level ≤ 5%

• Applications Notes:

  Each investigator should determine their own optimal working dilution for specific applications.

• Isotype Control:

  https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

• CAS Number:

  9007-83-4