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Itameline

CAT: 0804-HY-U00085-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00085-01Size:1 mg
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Description
Itameline (RU 47213) is a prodrug with oral and long-lasting cholinergic activity. Itameline is a novel tetrahydropyridine-oxime that is cleaved in vivo to form an active metabolite, RU 35963. RU 35963 is a muscarinic receptor agonist that is nonselective with respect to receptor subtypes. Itameline possesses the capacity to reduce memory deficits induced by an impairment of cholinergic transmission in the rat[1].
CAS Number
145071-44-9
Product Name Alternative
RU 47213
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/itameline.html
Smiles
O=C(N1CCC=C(/C=N/OC)C1)OC2=CC=C(Cl)C=C2
Molecular Formula
C14H15ClN2O3
Molecular Weight
294.73
References & Citations
[1]M M'Harzi, et al. Ameliorating effects of RU 47213, a novel oral and long-lasting cholinomimetic agent, on working memory impairments in rats. Pharmacol Biochem Behav. 1997 Apr;56 (4) :663-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
GTR19192807-01Itameline
M36185-01(EZ) -Itameline

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