Detomidine

• UNSPSC Description:

  Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects[1][2].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Neurological Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/detomidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C)C(CC2=CN=CN2)=CC=C1

• Molecular Weight:

  186.25

• References & Citations:

  [1]Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8(1):30-7.|[2]J Still, et al. Cardiovascular and respiratory effects of detomidine in isoflurane-anaesthetised horses. J S Afr Vet Assoc. 1996 Dec;67(4):199-203.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  76631-46-4