Detomidine

CAT: 804-HY-B0163-01Size: 10 mgDry Ice: NoHazardous: No
10 mgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects[1][2].
CAS Number
[76631-46-4]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/detomidine.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C)C(CC2=CN=CN2)=CC=C1
Molecular Formula
C12H14N2
Molecular Weight
186.25
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8 (1) :30-7.|[2]J Still, et al. Cardiovascular and respiratory effects of detomidine in isoflurane-anaesthetised horses. J S Afr Vet Assoc. 1996 Dec;67 (4) :199-203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

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