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PITPNB Antibody / PI-TP-beta

CAT: 0800-RQ7934Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7934Size:100 µg
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Description
Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene. This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P48739
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids Q148-R170) was used as the immunogen for the PITPNB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the PITPNB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PITPNB antibody is available for research use only.
Storage Conditions
After reconstitution, the PITPNB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PITPNB antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human esophageal squamous cell carcinoma tissue with PITPNB antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · P48739

Phosphatidylinositol transfer protein beta isoform

PIPNB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48739
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PITPNB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PI-TP-beta, PtdIns transfer protein beta, PtdInsTP beta
EC number
—
Processing
—
Secondary accessions
B3KYB8, B7Z7Q0, Q8N5W1
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulumGolgi apparatusMembrane

Biological process

Lipid transportTransport

Ligand

Lipid-binding

Technical term

Proteomics identificationReference proteome

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