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PACSIN2 Antibody

CAT: 0800-RQ7926Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7926Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein kinase C and casein kinase substrate in neurons protein 2 (Pacsin 2) is a protein that in humans is encoded by the PACSIN2 gene. This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9UNF0
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
E. coli-derived recombinant human protein (amino acids M84-D397) was used as the immunogen for the PACSIN2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the PACSIN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PACSIN2 antibody is available for research use only.
Storage Conditions
After reconstitution, the PACSIN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PACSIN2 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human lung cancer tissue with PACSIN2 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · Q9UNF0

Protein kinase C and casein kinase substrate in neurons protein 2

PACN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UNF0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PACSIN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoplasmic vesicleCytoskeletonEndosomeMembrane

Domain

Coiled coilSH3 domain

Biological process

Endocytosis

Ligand

Lipid-binding
Product Datasheet
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