SUCLA2 Antibody / Succinyl-CoA synthetase beta-A chain

SUCLA2 Antibody / Succinyl-CoA synthetase beta-A chain

• Description: Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (SUCLA2), also known as ADP-forming succinyl-CoA synthetase (SCS-A), is an enzyme that in humans is encoded by the SUCLA2 gene on chromosome 13. Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
• CAS Number: 9007-83-4
• UniProt: Q9P2R7
• Host: Rabbit
• Immunogen: E. coli-derived recombinant human protein (amino acids Q50-H454) was used as the immunogen for the SUCLA2 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IF, FACS, Direct ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the SUCLA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This SUCLA2 antibody is available for research use only.