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RGMB Antibody

CAT: 0800-F54118-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F54118-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Repulsive Guidance Molecule B is a member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity) . Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) . Promotes neuronal adhesion (By similarity) . May inhibit neurite outgrowth. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
Q6NW40
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant human RGMB was used as the immunogen for the RGMB antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RGMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RGMB antibody is available for research use only.
Storage Conditions
Aliquot the RGMB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the RGMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of RGMB antibody at 1:2000: Lane 1) human U-251 MG, 2) (h) HEK293, 3) (h) brain and 4) mouse brain lysate. Predicted molecular weight: 48-58 kDa.

UniProtKB · Q6NW40

Repulsive guidance molecule B

RGMB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6NW40
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RGMB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D6R9A0, Q8NC92
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinGPI-anchorLipoprotein

Cellular component

Cell membraneMembrane

Domain

Signal

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