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TLR6 Polyclonal Antibody

CAT: 0965-JOT-AP15007-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15007-01Size:20 µL
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Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
CAS Number
9007-83-4
Synonyms
Toll-like receptor 6; Toll-like receptor 6; CD286
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein of TLR6
Clonality
Polyclonal
Applications
IHC-p, IF
Stability
-20°C for 1 year
Antibody Type
Primary antibody
Isotype
IgG

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