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TF Polyclonal Antibody

CAT: 0965-JOT-AP14875-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14875-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Tissue factor; F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142
Host
Rabbit
Reactivity
Human, Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human Coagulation Factor III. AA range:246-295
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
33068
Antibody Type
Primary antibody
Isotype
IgG

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