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STAT2 Polyclonal Antibody

CAT: 0965-JOT-AP14535-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14535-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Signal transducer and activator of transcription 2 ;p113; Signal transducer and activator of transcription 2; p113
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human Stat2 around the non-phosphorylation site of Y631.
Clonality
Polyclonal
Applications
WB, IHC-p, IF
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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