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SCNBA Polyclonal Antibody

CAT: 0965-JOT-AP14080-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14080-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
CAS Number
9007-83-4
Synonyms
Sodium channel protein type 11 subunit alpha ;Peripheral nerve sodium channel 5;PN5;Sensory neuron sodium channel 2;Sodium channel protein type XI subunit alpha;Voltage-gated sodium channel su
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG