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RO52 Polyclonal Antibody

CAT: 0965-JOT-AP13871-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13871-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
CAS Number
9007-83-4
Synonyms
E3 ubiquitin-protein ligase TRIM21 ;EC 6.3.2.-;52 kDa Ro protein;52 kDa ribonucleoprotein autoantigen Ro/SS-A;RING finger protein 81;Ro;SS-A;Sjoegren syndrome type A antigen;SS-A;Tripar
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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