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RANK Polyclonal Antibody

CAT: 0965-JOT-AP13564-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13564-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
CAS Number
9007-83-4
Synonyms
Tumor necrosis factor receptor superfamily member 11A ;Osteoclast differentiation factor receptor;ODFR;Receptor activator of NF-KB;CD antigen CD265; Tumor necrosis factor receptor superfamily member 11A; Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD antigen CD265
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide from human protein at AA range: 60-120
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG