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PHC3 Polyclonal Antibody

CAT: 0965-JOT-AP12989-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12989-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 FCS-type zinc finger.,Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2.,
CAS Number
9007-83-4
Synonyms
Polyhomeotic-like protein 3 ;Early development regulatory protein 3;Homolog of polyhomeotic 3;hPH3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 720-800
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG