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PCBP2 Polyclonal Antibody

CAT: 0965-JOT-AP12842-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12842-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate
CAS Number
9007-83-4
Synonyms
Poly;rC-binding protein 2 ;Alpha-CP2;Heterogeneous nuclear ribonucleoprotein E2;hnRNP E2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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