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PARP-1 Polyclonal Antibody

CAT: 0965-JOT-AP12793-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12793-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
CAS Number
9007-83-4
Synonyms
Poly [ADP-ribose] polymerase 1; PARP1; ADPRT; PPOL; Poly [ADP-ribose; polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD;+ ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose; synthase 1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human PARP-1.
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
113084
Antibody Type
Primary antibody
Isotype
IgG