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P3C2B Polyclonal Antibody

CAT: 0965-JOT-AP12645-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12645-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.
CAS Number
9007-83-4
Synonyms
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta ;PI3K-C2-beta;PtdIns-3-kinase C2 subunit beta;EC 2.7.1.154;C2-PI3K;Phosphoinositide 3-kinase-C2-beta
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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