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OGG1 Polyclonal Antibody

CAT: 0965-JOT-AP12189-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12189-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
CAS Number
9007-83-4
Synonyms
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase ;EC 3.2.2.-; DNA-;apurinic or apyrimidinic site lyase ;AP lyase;EC 4.2.99.18]
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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