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NACA Polyclonal Antibody

CAT: 0965-JOT-AP11690-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP11690-01Size:20 µL
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Background
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
CAS Number
9007-83-4
Synonyms
Nascent polypeptide-associated complex subunit alpha ;NAC-alpha;Alpha-NAC;allergen Hom s 2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 100-180
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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