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KCNQ1 Polyclonal Antibody

CAT: 0965-JOT-AP10652-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP10652-01Size:20 µL
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Background
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
Potassium voltage-gated channel subfamily KQT member 1 ;IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1;KQT-like 1;Voltage-gated potassium channel subunit Kv7.1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 350-430
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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