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KCNN3 (SK3) Polyclonal Antibody

CAT: 0965-JOT-AP10650-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP10650-01Size:20 µL
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Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript v
CAS Number
9007-83-4
Synonyms
Small conductance calcium-activated potassium channel protein 3 ;SK3;SKCa 3;SKCa3;KCa2.3; Small conductance calcium-activated potassium channel protein 3; SK3; SKCa 3; SKCa3; KCa2.3
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthetic Peptide of KCNN3 (SK3)
Clonality
Polyclonal
Applications
IHC-p, IF
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG