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HES2 Polyclonal Antibody

CAT: 0965-JOT-AP09870-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09870-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).,The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.,Transcriptional repressor of genes that require a bHLH protein for their transcription.,Contains 1 basic helix-loop-helix (bHLH) domain.,Contains 1 Orange domain.,subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.,tissue specificity:Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.,
CAS Number
9007-83-4
Synonyms
Transcription factor HES-2 ;Class B basic helix-loop-helix protein 40;bHLHb40;Hairy and enhancer of split 2
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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