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Gl Syn Polyclonal Antibody

CAT: 0965-JOT-AP15736-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15736-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Gl Syn; Glutamine synthetase; GS; EC 6.3.1.2; Glutamate decarboxylase; EC 4.1.1.15; Glutamate--ammonia ligase
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Gl Syn. at AA range: 301-350
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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