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GFRA2 Polyclonal Antibody

CAT: 0965-JOT-AP09477-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09477-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
GDNF family receptor alpha-2 ;GDNF receptor alpha-2;GDNFR-alpha-2;GFR-alpha-2;GDNF receptor beta;GDNFR-beta;Neurturin receptor alpha;NRTNR-alpha;NTNR-alpha;RET ligand 2;TGF-beta-rela
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 320-400
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG