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Dsg1 Polyclonal Antibody

CAT: 0965-JOT-AP08632-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08632-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
CAS Number
9007-83-4
Synonyms
Desmoglein-1; DSG1; CDHF4; Desmoglein-1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DSG1. AA range:161-210
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
113748
Antibody Type
Primary antibody
Isotype
IgG

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