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Crystallin-alphaC Polyclonal Antibody

CAT: 0965-JOT-AP08140-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08140-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
CAS Number
9007-83-4
Synonyms
Heat shock protein beta-8; HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Protein of Crystallin-αC
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Antibody Type
Primary antibody
Isotype
IgG

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