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CLCN1 Polyclonal Antibody

CAT: 0965-JOT-AP07773-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07773-01Size:20 µL
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Background
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Chloride channel protein 1 ;ClC-1;Chloride channel protein, skeletal muscle
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG