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CD152 Polyclonal Antibody

CAT: 0965-JOT-AP14798-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14798-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
CAS Number
9007-83-4
Synonyms
Cytotoxic T-lymphocyte protein 4 ;Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD antigen CD152; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide from human protein at AA range: 41-90
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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