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ABCC8 Polyclonal Antibody

CAT: 0965-JOT-AP14026-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14026-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy| an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II| an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for
CAS Number
9007-83-4
Synonyms
ATP-binding cassette sub-family C member 8 ;Sulfonylurea receptor 1
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 500-580
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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