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XPC Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP05520-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05520-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc. This component| XPC| plays an important role in the early steps of global genome NER| especially in damage recognition| open complex formation| and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
XPC
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human XPC
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
103400
Antibody Type
Primary antibody
Isotype
IgG