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SSRP1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP04909-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04909-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a subunit of a heterodimer that| along with SUPT16H| forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described| but its full-length nature is not known.
CAS Number
9007-83-4
Synonyms
SSRP1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human SSRP1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
77990
Antibody Type
Primary antibody
Isotype
IgG