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SPTN2 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP04875-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04875-01Size:20 µL
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Background
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2)| is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to| but distinct from| the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia| SCA5| that is characterized by neurodegeneration| progressive locomotor incoordination| dysarthria| and uncoordinated eye movements.
CAS Number
9007-83-4
Synonyms
SPTN2
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from human SPTN2
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
262900
Antibody Type
Primary antibody
Isotype
IgG

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