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SPTA1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP04870-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04870-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton| and functions in the determination of cell shape| arrangement of transmembrane proteins| and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin| which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders| including elliptocytosis type 2| pyropoikilocytosis| and spherocytic hemolytic anemia.
CAS Number
9007-83-4
Synonyms
SPTA1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human SPTA1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
266090
Antibody Type
Primary antibody
Isotype
IgG