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SNX13 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP12702-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12702-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain| and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s)| accelerates its GTP hydrolysis| and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role| this protein may link heterotrimeric G protein signaling and vesicular trafficking.
CAS Number
9007-83-4
Synonyms
SNX13; Sorting nexin-13; RGS domain- and PHOX domain-containing protein; RGS-PX1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human SNX13
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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