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SELH Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP04690-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04690-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a nucleolar protein| which belongs to the SelWTH family. It functions as an oxidoreductase| and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways| promote mitochondrial biogenesis and mitochondrial function| and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein| containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon| which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure| designated the Sec insertion sequence (SECIS) element| that is necessary for the recognition of UGA as a Sec codon| rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
SELH
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human SELH
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
13420
Antibody Type
Primary antibody
Isotype
IgG