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RUBIC Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP12356-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12356-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains| an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling| and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
RUBIC; Run domain Beclin-1 interacting and cystein-rich containing protein; Rubicon; Beclin-1 associated RUN domain containing protein; Baron
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human RUBIC
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG