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RFX6 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP04450-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04450-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function| thus| restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome| which is characterized by neonatal diabetes with pancreatic hypoplasia| duodenal and jejunal atresia| and gall bladder agenesis.
CAS Number
9007-83-4
Synonyms
RFX6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human RFX6
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
102080
Antibody Type
Primary antibody
Isotype
IgG